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View Full Version : Two genetic variants who tell if your big toe or second toe will be the longest one


jibarodepr
2011-08-16, 20:47
https://www.23andme.com/about/factoids/



For most people the big toe, is the longest toe, but for some people the second, or "pointer" toe, is longer. Scientists at 23andMe have now identified two genetic variants associated with the relative sizes of the big toe and pointer toe. In our customers who have European ancestry, the A version of rs143383 (https://www.23andme.com/you/explorer/snp/?snp_name=rs143383) and the T version of rs1479643 (https://www.23andme.com/you/explorer/snp/?snp_name=rs1479643) are both associated with slightly higher odds of having a longer big toe. One of these variants is in a gene called GDF5, which is believed to be involved in skeletal development.


What do you think about this genetic discovery?
Dave
2011-08-16, 21:04
so Europeans have a longer big toe usually?
Lemminkäinen
2011-08-16, 21:14
I am GG/CC and my toes are equal length.
Chalybus
2011-08-16, 21:19
Would be interesting if there are statistics broken down by ethnicity. For most people I have seen here in the region the second toe is the longest. And so for me, despite being AA / TT
timmay
2011-08-16, 21:21
so Europeans have a longer big toe usually?

No, the reference to Europeans (actually people who >90% West Eurasian) is because these health results are usually relavant to this group due to the research testing-so 23andme always have to put a disclaimer that the health results are relevant to people of 'European' ancestry (again, by which they mean people who are predom West Eurasian).
jibarodepr
2011-08-17, 04:04
My first toe(the big one) is the longest.
Aino
2011-08-17, 05:11
I am AG/CC, and my big toe is the longest.
annihilus
2011-08-17, 05:59
AG/CT my second toe is longer
ethioboy
2011-08-17, 06:15
gg/tt they are the same length.. which corresponds to my genotype.
FeistyGermanGhost
2012-06-12, 03:43
rs143383-AA


rs1479643 -CC

Second toe is slightly longer than big toe.
Sea Warrior 86
2012-06-14, 04:50
https://www.23andme.com/about/factoids/
What do you think about this genetic discovery?

I personally think that this "discovery" may not be that accurate, because I am AA/TT and my second toe is slightly longer than my big toe. If 23andMe's prediction was correct then it should be the other way around.

However, I do find these kinds of test interesting and am glad that 23andMe is looking into explaining physical anthropology from genetics.
snowwhite
2012-06-15, 05:46
AA/TT, second is longer.