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Thread: BIG STUDY! In depth Y- & mtDNA Analysis of Ethiopians1673 days old

  1. #1
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    Default BIG STUDY! In depth Y- & mtDNA Analysis of Ethiopians

    This study is actually from last year. It includes Nilo-Saharan, Cushitic, Omotic & Semitic speakers!

    Abstract

    There is a paucity of genetic studies of Ethiopia. This thesis aims to establish the extent and distribution of variation in NRY and mtDNA genetic markers as well as ethnic and linguistic labels of identity 45 ethnic groups. A wide range of NRY and mtDNA haplogroups were observed, including both those typically observed in Africa and those more frequently observed outside Africa. Significant correlations were revealed between NRY and mtDNA diversity. Nearly all ethnic groups were significantly differentiated from each other, although the pattern of similarities indicates some recent gene flow between northern ethnic groups and some groups to the south. Significant correlations were observed between almost all measures of linguistic and ethnic similarity and measures of NRY and mtDNA genetic distance. A wide range of values for diversity of sample donors' ethnic and linguistic identity was observed across groups. There was no evidence that the language of the sample donor is more likely to be inherited from parents of one sex rather than the other. There was a general decrease in the proportion of sample donors speaking the traditional language of their ethnic groups compared with the donor's parents and grandparents, with a corresponding increase in the proportion of sample donors speaking Amhara as a first language. Restricting analysis to samples from donors with ethnic identity in common with their parents and grandparents had significant effects on the degree of genetic distinctiveness of ethnic groups. Increasing the level of resolution of NRY and mtDNA haplotypes did not substantially alter the patterns of diversity and distance observed in and amongst ethnic groups. This thesis makes an important contribution to understanding the distribution of genetic diversity in Ethiopia.
    This is a LONG read, but VERY informative:
    http://discovery.ucl.ac.uk/1331901/
    http://discovery.ucl.ac.uk/1331901/3...-POST-VIVA.pdf



    • AF = Afar (Cushitic, Afar region: 2)
    • AM = Amhara (Semitic, Amhara region: 3)
    • AN = Anuak (Nilotic, Gambela: 6)
    • ML = Maale (Omotic, SPNN region: 10)
    • OR = Oromo (Cushitic, Oromia: 8)





    • AF = Afar (Cushitic, Afar region: 2)
    • AM = Amhara (Semitic, Amhara region: 3)
    • AN = Anuak (Nilotic, Gambela: 6)
    • ML = Maale (Omotic, SPNN region: 10)
    • OR = Oromo (Cushitic, Oromia: 8)






    • All M is M1 (overall: 10%, AM 17%, OR 13%, AF 9%, ML 6%)
    • R0(xHV) reaches 11% among the Amhara (all R0: 15%)
    • N1 reaches 7% among the Afar
    • U(xK) reaches 6% among the Afar (all U: 9%)
    • K reaches 6% among the Maale (all U: 9%)
    Last edited by pgbk87; 2012-11-27 at 15:10.

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    Armor King (2012-12-02), beyoku (2012-11-27), chicken (2012-11-27), Doctoris Scientia (2012-11-27), Hweinlant (2012-11-27), Lol_Race (2012-11-27), modernsappho (2012-11-28), Sargon999 (2012-11-27), Zakar-Baal (2012-11-27)

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    Wow, that's a lot of data! Will have to look through it all thoroughly.

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    Good find!

    Is the P*(xR1a) at fig 3.2 R1b ?

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    Quote Originally Posted by Hweinlant View Post
    Good find!

    Is the P*(xR1a) at fig 3.2 R1b ?
    I don't think P*(xR1a) was identified in any of the samples, you're probably looking at BT*(xDE,JT).

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    http://4.bp.blogspot.com/-Vy1WbkI0OI.../s1600/NRY.PNG

    1. AN: Anuak (Nilotic)
    2. NR: Nuer (Nilotic)
    3. SC: Sheckecho (Omotic)
    4. GE: Gedeo (East Cushitic)
    5. KF: Kefa (Omotic)
    6. AL: Alaba (East Cushitic)
    7. GR: Gurange (South Ethio-Semitic)
    8. TG: Tigrinya (North Ethio-Semitic)
    9. AM: Amhara (South Ethio-Semitic)
    10. AG: Agaw (Central Cushitic)
    11. OR: Oromo (South Cushitic)
    12. YM: Yem (Omotic)
    13. AF: Afar (East Cushitic)
    14. KM: Kembata (East Cushitic)
    15. SM: Somali (East Cushitic)
    16. WL: Wolayta (Omotic)
    17. KN: Konta (Omotic)
    18. GM: Gamo (Omotic)
    19. DR: Dorze (Omotic)
    20. GF: Gofa (Omotic)
    21. DW: Dawuro (Omotic)
    22. HD: Hadiya (East Cushitic)
    23. BN: Bench (Omotic)
    24. GW: Gewada (East Cushitic)
    25. SD: Sidama (East Cushitic)
    26. DI: Dirasha (East Cushitic)
    27. KR: Kore (Omotic)
    28. BR: Burji (East Cushitic)
    29. HM: Hamer (Omotic)
    30. BE: Bena (Omotic)
    31. KS: Konso (East Cushitic)
    32. MH: Mashile (East Cushitic)
    33. TY: Tesemay (East Cushitic)
    34. DS: Dasanach (East Cushitic)
    35. BU: Busa (East Cushitic)
    36. BK: Basketo (Omotic)
    37. ML: Maale (Omotic)
    38. DZ: Dizi (Omotic)
    39. GN: Ganjule (Omotic)
    40. MG: Majangir (Nilo-Saharan)
    41. AA: Ari (Omotic)
    42. ZS: Zayse (Omotic)
    43. GB:Gobeze (Omotic)
    44. SK: Sheko (Omotic)
    45. GG: Genta (Omotic)
    Last edited by Doctoris Scientia; 2012-11-27 at 17:37.

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    • The Y-DNA profile of the Nilotic Anuak compared to the Nuer is stiking to say the least. The Nuer are only about 2-3% E1b1a7, while the Anuak are more like 40%!
    • There Somali sample set came back ~30% Y-DNA "K" (T1a really).
    • Omotic groups are Y-DNA E (xE1b1a) at atleast 70%!
    Last edited by pgbk87; 2012-11-27 at 17:35.

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    Great find! The Somalis were Ogaden Ethio Somalis I presume?

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    Quote Originally Posted by chicken View Post
    Great find! The Somalis were Ogaden Ethio Somalis I presume?
    I would guess so. Do you see how high the occurence of Y-DNA "K" (T1a) is?

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    Quote Originally Posted by pgbk87 View Post
    • The Y-DNA profile of the Nilotic Anuak compared to the Nuer is stiking to say the least. The Nuer are only about 2-3% E1b1a7, while the Anuak are more like 40%!
    • There Somali sample set came back ~30% Y-DNA "K" (T1a really).
    • Omotic groups are Y-DNA E (xE1b1a) at atleast 70%!
    The Nilo-Saharan Manajir are also very different from the Anuak and Nuer.

    The high J frequencies in some of the Omotic groups is also interesting.

    ---------- Post Merged at 17:41 ----------

    Quote Originally Posted by pgbk87 View Post
    I would guess so. Do you see how high the occurence of Y-DNA "K" (T1a) is?
    How many Somalis were sampled in this study? It could be founder affect, since their T1a frequency is relatively higher than expected.
    Last edited by Doctoris Scientia; 2012-11-27 at 17:44.

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    Quote Originally Posted by Doctoris Scientia View Post
    The Nilo-Saharan Manajir are also very different from the Anuak and Nuer.
    Yeah. Nilo-Saharan's are a confusing bunch lol. But next to no Y-DNA J lol

    The high J frequencies in some of the Omotic groups are also interesting.
    Yeah, but it can explained by interaction with Ethio-Semitic speakers. Not surprising

    How many Somalis were sampled?
    108. Take that 30% with a grain of salt lol

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