User Tag List

Results 1 to 7 of 7

Thread: Brain fog and genetic mutations, please help if you can.541 days old

  1. #1
    Junior Member
    Last Online
    2016-11-01 @ 06:33
    Join Date
    2016-11-01
    Posts
    1
    Gender

    Default Brain fog and genetic mutations, please help if you can.

    Hello, for the last year I've felt that my mental functioning has been slowing down and is not quite what it used to be. I'm only 25 and I notice that simple questions will take me longer to answer and I have quite a bit of mental strain. I know this is partly due to habits and negative self-talk. I am a totally different person, and I do not like myself at all. So please, any suggestions you have would be greatly apperciated. Any supplements, lifestyle changes, or anything in between.. I'm willing to do anything to return to who I was.

    However, I did a 23andme a ~7 months ago to hopefully get some insight as to what is going on. I found out I have quite a bit of mutations but upon research, it seemed to be nothing out of the ordinary. I did however notice that Nutrahacker,promethease,genetic genie, and livewello stated that, perhaps, methylated b vitamins may help (nutrahacker was the opposite 3/4 recommendations said to avoid methylated compounds).

    I started taking 5000mcg methylcobalamin, 800 mcg methylfolate. I was taking Jarrow's b-right and a methylated multi called BioVite. That seemed too much. I lowered the dose to just the Biovite (250mcg methylcobalamin and 400mcg of methylfolate).

    I do feel better after making the change, but it's only a tad better and I am experiencing worse symptoms from taking methylated vitamins.

    My question is, was nutrahacker correct? Should I avoid most methylated compounds and switch to adenosylcobalamin or Hydroxocobalamin and switch the methylfolate to folinic acid?

    I live a fairly healthy lifestyle. I do not eat processed foods, I don't eat gluten (I am currently testing for gluten sensitivity), gut health, nootropics, water consumption, I workout 5 days a week, watch my blood sugar, have no added sugar, herbal supplements... at this point I don't know what to do.

    I want to shake this fog i'm in.. for the last year I've have this unshakable depression, brain fog and overall low motivation. I was the polar opposite of this. Please, if it's within your power to help, do so; I will pay it forward..believe me.

    homozygous mutations:
    CYP2D6 S486T (GG)
    VDR Bsm (TT)
    MAO A R297R (T)
    CBS C699T (AA)


    heterozygous mutations:
    COMT V158M (AG)
    COMT H62H (CT)

    MTHFR C677T (AG)
    MTR A2756G (AG)
    MTRR A66G (AG)
    MTRR A664A (AG)

    BHMT-02 (CT)
    BHMT-08 (CT)

    AHCY-01 (CT)
    AHCY-19 (CT)

    CYP1A2 164A>C (AC)
    CYP1B1 L432V (CG)
    CYP1B1 N453S (CT)
    CYP1B1 R48G (CG)
    CYP2A6*2 1799T>A (AT)
    CYP2D6 100C>T (AG)
    CYP2D6 2850C>T (AG)
    CYP2C19*17 (CT)



    Thank you very much. I really appreciate any and every response

  2. # ADS
    Advertisement bot
    Join Date
    2013-03-24
    Posts
    All threads
       
     

  3. #2
    Established Member
    Member / DNA Hobbyist thetick's Avatar
    Last Online
    Today @ 04:01
    Join Date
    2011-12-27
    Posts
    2,454
    Location
    USA
    Gender
    Y-DNA
    R1b-SRY 2627 - A7080
    mtDNA
    H5a1f
    Phenotype
    Archaic Nomenclature
    Politics
    Not a Fan
    GEDmatch
    M202348
    United States Germany Poland Poland Volhynia Switzerland Scotland

    Default

    Everyone has lots of mutations otherwise we would not be different?

    Ok. Send me $100 and my handcrafted snake oil will cure all your problems or your money back.

    Seriously stop chasing quacks and fads. Go to a real doctor. The internet is a terrible place to get answers to your questions above as too far many will just want to sell you something worthless especially when state you are willing to pay? WTH !
    Last edited by thetick; 2016-11-01 at 07:13.

  4. #3
    Established Member
    Molecular Biologist CrazyDaisy's Avatar
    Last Online
    Today @ 06:14
    Join Date
    2016-05-03
    Posts
    834
    Location
    Canada
    Gender
    mtDNA
    U5b3f
    Canada Ecuador Galicia Basque Germany Peru

    Default

    Try Brain Octane. It really helps clear up my brain.

  5. #4
    Established Member
    Molecular Biologist ThePendragon's Avatar
    Last Online
    2017-07-26 @ 22:31
    Join Date
    2016-10-05
    Posts
    1,131
    Location
    New York
    Gender
    Y-DNA
    R1b-Z253 >Z6749.1
    mtDNA
    H
    Phenotype
    Atlantid
    Metaethnos
    Celto-Germanic
    Ethnicity
    mainstream American
    Politics
    conservative
    Religion
    pantheist
    United States Northern Ireland Germany Scotland Ireland England
    American of Scots-Irish or Ulster Ancestry :

    'I am a Scotsman', Sir Walter Scott once famously wrote, ' therefore I had to fight my way into the world'.

    "Of all the small nations of this earth, perhaps only the ancient Greeks surpass the Scots in their contribution to mankind.” --Winston Churchill(England)

    "We look to Scotland for all our ideas of civilisation.” --Voltaire(France)

  6. #5
    Established Member
    Molecular Biologist
    Last Online
    @
    Join Date
    2012-08-07
    Posts
    698
    Gender
    Race
    Caucasoid
    Metaethnos
    Levantine
    Ethnicity
    Lost Samaritan
    Politics
    Anarcho-capitalism
    Religion
    Eugenics
    Palestine United States

    Default

    Are you sure it's not depression OP? Processing speed is hindered substantially when suffering from depression.
    Last edited by randomguy1235; 2016-11-03 at 02:35.

  7. #6
    Established Member
    Molecular Biologist ThePendragon's Avatar
    Last Online
    2017-07-26 @ 22:31
    Join Date
    2016-10-05
    Posts
    1,131
    Location
    New York
    Gender
    Y-DNA
    R1b-Z253 >Z6749.1
    mtDNA
    H
    Phenotype
    Atlantid
    Metaethnos
    Celto-Germanic
    Ethnicity
    mainstream American
    Politics
    conservative
    Religion
    pantheist
    United States Northern Ireland Germany Scotland Ireland England

    Default

    Quote Originally Posted by randomguy1235 View Post
    Are you sure it's not depression OP? Processing speed is hindered substantially when suffering from depression.
    Depression can be cured with the following, if that is the case, please see below :

    L-tyrosine
    Sub-adrene
    Zinc
    Taurine
    Essential fatty acids
    Vitamin B complex
    Vitamin B-6
    Vitamin B-12
    Vitamin B-5
    Folic acid
    Choline and inosital
    GH4
    Calcium and magnesium
    Chromium
    Gaba
    Lithium
    Last edited by ThePendragon; 2016-11-03 at 05:42.
    American of Scots-Irish or Ulster Ancestry :

    'I am a Scotsman', Sir Walter Scott once famously wrote, ' therefore I had to fight my way into the world'.

    "Of all the small nations of this earth, perhaps only the ancient Greeks surpass the Scots in their contribution to mankind.” --Winston Churchill(England)

    "We look to Scotland for all our ideas of civilisation.” --Voltaire(France)

  8. #7
    Senior Moderator
    Plant of Life = Biological Magic 麻 EliasAlucard's Avatar
    Last Online
    @
    Join Date
    2009-10-22
    Posts
    13,984
    Location
    Sweden
    Gender
    Age
    33
    Y-DNA
    J1a2a1a2-P58+
    mtDNA
    H5a
    Race
    Caucasian
    Phenotype
    Alpinid
    Metaethnos
    proto-Semitic
    Ethnicity
    Assyrian/Armenian
    Politics
    Environment, Cannabis
    Religion
    Secular Agnostic
    Assyria Assyria 1913-1923 Armenia Lebanon Sweden Greece

    Default

    Quote Originally Posted by braingains22 View Post
    I started taking 5000mcg methylcobalamin, 800 mcg methylfolate. I was taking Jarrow's b-right and a methylated multi called BioVite. That seemed too much. I lowered the dose to just the Biovite (250mcg methylcobalamin and 400mcg of methylfolate).

    I do feel better after making the change, but it's only a tad better and I am experiencing worse symptoms from taking methylated vitamins.

    My question is, was nutrahacker correct? Should I avoid most methylated compounds and switch to adenosylcobalamin or Hydroxocobalamin and switch the methylfolate to folinic acid?
    5 mg of methylcobalamin is great, and it's the most superior form of B12. You might want to try a combination of methylcobalamin and adenosylcobalamin, see if that works better. Also make sure you supplement with methylfolate, and not folic acid. If this still doesn't work, I recommend some high dosages of vitamin D3, like at least 10,000 IUs per day. Don't forget vitamin K2 also, and some retinyl palmitate.
    ReactOS <--- support this project so that we can get rid of Windows!
    Ubuntu MATE 16.04.1 LTS | PRISM-Break! | Windows7sins

    “A wise man makes his own decisions; an ignorant man follows public opinion.” ― Chinese proverb

    “Every decent man is ashamed of the government he lives under.” ― H. L. Mencken

    “The only good is knowledge and the only evil is ignorance.” ― Socrates

    “Damnant quod non intelligunt.” ― Latin proverb

    Quoted for truth:
    Quote Originally Posted by Alaron View Post
    Anatolian Urhemait supporters are mostly butthurt Meds.
    For the lulz:
    Quote Originally Posted by drgs View Post
    Poland is a misunderstanding. It is a country which lies on the frontier between western and slavic world, and which combines elements of both.
    In fact, they are not even the Europeans in strict sense, meaning European as in bearing the responsibility and understanding of European interests. Poland has always been an subordinate country, on one side sucking German dick, on the other side -- Russian one, some kind of "novice" europeans, who are full of inferiority complexes, hysteria and obsessity neuroses. This is also true for all Baltic countries

Similar Threads

  1. Right Brain vs Left Brain test
    By safinator in forum Behavioural Neuroscience
    Replies: 35
    Last Post: 2012-10-13, 17:44
  2. How can I see Required Mutations in 23 and Me snp file?
    By modernsappho in forum General Genetics Discussion
    Replies: 2
    Last Post: 2012-02-22, 17:25
  3. Gene Activity in the Brain Depends on Genetic Background
    By warwick in forum Ancestry & Health
    Replies: 0
    Last Post: 2010-11-03, 06:06
  4. What caused genetic mutations that gave rise to different races?
    By Sorber in forum General Genetics Discussion
    Replies: 3
    Last Post: 2010-09-29, 08:14
  5. The Right Brain vs Left Brain test
    By takoja in forum Behavioural Neuroscience
    Replies: 50
    Last Post: 2010-08-18, 06:07

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
<